GALE anticorps (Middle Region)

N° du produit ABIN928723

Cet anticorps Lapin Polyclonal détecte spécifiquement GALE dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GALE anticorps (Middle Region) (ABIN928723)

Antigène: GALE (UDP-Galactose-4-Epimerase (GALE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GALE est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GALE anticorps

Épitope: Middle Region

Purification: Purified

Immunogène: GALE antibody was raised in rabbit using the middle region of GALE as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

GALE Blocking Peptide, (ABIN5613709), is also available for use as a blocking control in assays to test for specificity of this GALE antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur GALE

Antigène: GALE (UDP-Galactose-4-Epimerase (GALE))

Autre désignation: GALE

Sujet: GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild to severe ('generalized' form). Synonyms: Polyclonal GALE antibody, Anti-GALE antibody, UDP-galactose-4-epimerase antibody.

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process