ABL1 anticorps (AA 577-650)

N° du produit ABIN931298

L’anticorps anti-ABL1 Monoclonal Souris est utilisé pour la détection de ABL1 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour ABL1 anticorps (AA 577-650) (ABIN931298)

Antigène: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ABL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 7B11D6

Détail du produit anti-ABL1 anticorps

Épitope: AA 577-650

Immunogène: ABL1 antibody was raised in Mouse using a purified recombinant fragment of ABL1(aa577-650) expressed in E. coli as the immunogen.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Détails sur ABL1

Antigène: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Autre désignation: ABL1

Sujet: The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of ABL1 protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9,22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes, leading to a fusion gene present in many cases of chronic myelogenous leukemia. Synonyms: Monoclonal ABL1 antibody, Anti-ABL1 antibody, V-abl Abelson murine leukemia viral oncogene homolog 1 antibody.

Pathways: Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism