Cet anticorps anti-FGFR4 Monoclonal Souris (Clone 4H2B10B2) (ABIN931323) détecte spécifiquement FGFR4 dans WB, ELISA et IHC.
L’anticorps est réactif avec des échantillons de Humain.
FGFR4 is part of a family of fibroblast growth factor receptors that mediate the biological functions of specific growth factors. Each receptor contains an extracellular ligand binding domain, a transmembrane domain and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. FGFR4 may also play a role in the development and maintenance of specialized cells (called foveal cones) in the retina. Synonyms: Monoclonal FGFR4 antibody, Anti-FGFR4 antibody, FGFR-4 antibody, FGFR 4 antibody, Fibroblast growth factor receptor 4 antibody.