BCL3 anticorps

N° du produit ABIN933151

Cet anticorps Souris Monoclonal détecte spécifiquement BCL3 dans WB, ICC et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour BCL3 anticorps (ABIN933151)

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL3 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Dot Blot (DB)

Clone: 2069E2a

Détail du produit anti-BCL3 anticorps

Réactivité croisée: Humain, Souris, Rat (Rattus)

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: BCL3 antibody was raised in mouse using recombinant Human B-Cell Cll/Lymphoma 3 (Bcl3)

Isotype: IgG1

Information d'application

Indications d'application: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: BCL3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur BCL3

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Autre désignation: BCL3

Sujet: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. Synonyms: Monoclonal BCL3 antibody, Anti-BCL3 antibody, B-cell lymphoma 3 encoded protein antibody, BCL4 antibody, D19S37 antibody.

Pathways: Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus