MICA anticorps
Aperçu rapide pour MICA anticorps (ABIN94331)
Antigène
Voir toutes MICA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-HLA Class I Purified
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Specificité
- The antibody MEM-81 reacts with an extracellular epitope on human classical MHC Class I molecules in native cell-surface forms. MHC Class I molecules (MHC Class Ia) are expressed on the surface of human nucleated cell types.
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Réactivité croisée (Details)
- Human
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Purification
- Purified by protein-A affinity chromatography.
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Pureté
- > 95 % (by SDS-PAGE)
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Immunogène
- Leukocytes of a patient suffering with LGL type leukemia.
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Isotype
- IgG1
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Indications d'application
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Autre désignation
- HLA Class I
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Sujet
- HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
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Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Antigène
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