Aspartate beta Hydroxylase anticorps (Middle Region)

N° du produit ABIN950540

Détail du produit anti-Aspartate beta Hydroxylase anticorps

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Épitope: AA 301-331, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aspartate beta Hydroxylase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to ASPH.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 301-331 amino acids from the Central region of human ASPH

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Aspartate beta Hydroxylase

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Autre désignation: ASPH (ASPH Produits)

Synonymes: anticorps AAH, anticorps BAH, anticorps CASQ2BP1, anticorps HAAH, anticorps JCTN, anticorps junctin, anticorps 2310005F16Rik, anticorps 3110001L23Rik, anticorps AI848629, anticorps AW261690, anticorps AW561901, anticorps C79816, anticorps cI-37, anticorps aah, anticorps bah, anticorps jctn, anticorps MGC107896, anticorps cb971, anticorps fb69e10, anticorps fc06d04, anticorps fc95a08, anticorps wu:fb69e10, anticorps wu:fc06d04, anticorps wu:fc95a08, anticorps aspartate beta-hydroxylase, anticorps aspartate-beta-hydroxylase, anticorps aspartate beta-hydroxylase L homeolog, anticorps ASPH, anticorps Asph, anticorps asph, anticorps asph.L

Sujet: This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.Synonyms: ASP beta-hydroxylase, Aspartate beta-hydroxylase, Aspartyl/asparaginyl beta-hydroxylase, HAAH, JCTN, Peptide-aspartate beta-dioxygenase, junctin

ID gène: 444

NCBI Accession: NP_001158222

Pathways: Positive Regulation of Endopeptidase Activity