Axin anticorps (C-Term)
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- Antigène Voir toutes Axin (AXIN1) Anticorps
- Axin (AXIN1) (Axin 1 (AXIN1))
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Épitope
- AA 717-746, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Axin est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to Axin-1.
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography on Protein A
- Immunogène
- KLH conjugated synthetic peptide between 717-746 amino acids from the C-terminal region of human AXIN1
- Isotype
- Ig Fraction
- Top Product
- Discover our top product AXIN1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) sodium azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- Axin (AXIN1) (Axin 1 (AXIN1))
- Autre désignation
- Axin-1 (AXIN1 Produits)
- Synonymes
- anticorps AXIN1, anticorps axin, anticorps fused, anticorps xAxin, anticorps LOC100226467, anticorps AXIN, anticorps PPP1R49, anticorps AI316800, anticorps Axin, anticorps Fu, anticorps Kb, anticorps Ki, anticorps kinky, anticorps knobbly, anticorps AXIN1-RGS, anticorps wu:fi22e03, anticorps wu:fj14c08, anticorps wu:fk11b03, anticorps zgc:109872, anticorps axin 1, anticorps axin 1 S homeolog, anticorps axin 1 L homeolog, anticorps AXIN1, anticorps axin1.S, anticorps axin1.L, anticorps Axin1, anticorps axin1
- Sujet
- This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene.Synonyms: AXIN, AXIN1, Axis inhibition protein 1
- ID gène
- 8312
- NCBI Accession
- NP_003493
- Pathways
- Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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