Cholesterol Esterase anticorps (Middle Region)

N° du produit ABIN950601

Cet anticorps anti-Cholesterol Esterase Polyclonal Lapin (ABIN950601) détecte spécifiquement Cholesterol Esterase dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Cholesterol Esterase anticorps (Middle Region) (ABIN950601)

Antigène: Cholesterol Esterase (CEL)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cholesterol Esterase est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Cholesterol Esterase anticorps

Épitope: AA 453-482, Middle Region

Specificité: This antibody recognizes Human CEL. Other species not tested.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 453-482 amino acids from the Central region of human CEL

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Cholesterol Esterase

Antigène: Cholesterol Esterase (CEL)

Autre désignation: BAL / CEL

Sujet: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.Synonyms: BSDL, BSSL, Bile salt-activated lipase, Bile salt-stimulated lipase, Bucelipase, CELL, CEase, Carboxyl ester lipase, Cholesterol esterase, FAP, FAPP, LIPA, MODY8, Pancreatic lysophospholipase, Sterol esterase

Poids moléculaire: 79322 Da

ID gène: 1056

NCBI Accession: NP_001798

Pathways: Lipid Metabolism