C5AR1 anticorps (Biotin)

N° du produit ABIN951419

Détail du produit anti-C5AR1 anticorps (Biotin)

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp C5AR1 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Specificité: This monoclonal antibody detects an epitope on the N terminus (aa 1-15) of the human C5a receptor (also known as CD88) found on human myeloid cells including granulocytes and monocytes/macrophages. It does not bind to tubular epithelial cells in situ under normal or inflammatory conditions. C5aR binds to C5a, a 74 aa peptide cleaved from complement protein C5. C5a receptor has seven transmembrane segments and is a member of the rhodopsin subfamily of G protein coupled receptors.

Purification: Affinity chromatography on Protein G

Immunogène: RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface Donor: Lou/c rat spleen cells

Clone: 8D6

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0,1 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C5AR1

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Autre désignation: CD88 / C5R1 (C5AR1 Produits)

Synonymes: anticorps C5A, anticorps C5AR, anticorps C5R1, anticorps CD88, anticorps C5aR, anticorps C5r1, anticorps Cd88, anticorps D7Msu1, anticorps GPR77, anticorps complement C5a receptor 1, anticorps complement component 5a receptor 1, anticorps C5AR1, anticorps C5ar1, anticorps c5ar1

Sujet: Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1

ID gène: 728

NCBI Accession: NP_001727

UniProt: P21730

Pathways: Système du Complément