CLASP2 anticorps (AA 1005-1034)
Aperçu rapide pour CLASP2 anticorps (AA 1005-1034) (ABIN951541)
Antigène
Voir toutes CLASP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1005-1034
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Réactivité croisée (Details)
- Species reactivity (tested):Human and Mouse.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 1005~1034 amino acids from the Y1019 region of human CLASP2
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
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Autre désignation
- CLASP2
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Sujet
- CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.Synonyms: CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, KIAA0627, Protein Orbit homolog 2, hOrbit2
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Poids moléculaire
- 141133 Da
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ID gène
- 9606
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Pathways
- Dynamique des Microtubules, Maintenance of Protein Location
Antigène
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