Complement Factor B anticorps (Middle Region)

N° du produit ABIN951644

L’anticorps Lapin Polyclonal anti-Complement Factor B a été validé pour WB, IHC (p) et EIA. Il convient pour détecter Complement Factor B dans des échantillons de Humain et Souris.

Aperçu rapide pour Complement Factor B anticorps (Middle Region) (ABIN951644)

Antigène: Complement Factor B (CFB)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement Factor B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Complement Factor B anticorps

Épitope: AA 474-504, Middle Region

Specificité: This antibody reacts to CFB.

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 474~504 amino acids from the Center region of human CFB

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Complement Factor B

Antigène: Complement Factor B (CFB)

Autre désignation: Complement Factor B

Sujet: CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

Poids moléculaire: 85533 Da

ID gène: 629

NCBI Accession: NP_001701

Pathways: Système du Complément, Proton Transport, Ribonucleoside Biosynthetic Process