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Cortactin anticorps (N-Term)
CTTN
Reactivité: Humain
WB, IHC (p), EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-Cortactin anticorps
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Antigène
Voir toutes Cortactin (CTTN) Anticorps
Cortactin (CTTN)
Épitope
Tous les épitopes à travers Cortactin Anticorps.
AA 16-46, N-Term
Reactivité
Toutes les réactivités sur Cortactin Anticorps
Humain
Hôte
Toutes les hôtes sur Cortactin Anticorps
Lapin
Clonalité
Toutes les clonalités sur Cortactin Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Cortactin Anticorps
Cet anticorp Cortactin est non-conjugé
Application
Tous les applications à travers Cortactin Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificité
This antibody recognizes Cortactin (SRC8) at N-term.
Réactivité croisée (Details)
Species reactivity (tested):Human
Purification
Purified through a Protein A column followed by peptide affinity purification
Immunogène
Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 16-46aa) of human Cortactin (SRC8)
Isotype
Ig Fraction
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur Cortactin
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Antigène
Cortactin (CTTN)
Autre désignation
Cortactin (CTTN Produits )
Synonymes
anticorps EMS1, anticorps 1110020L01Rik, anticorps Ems1, anticorps Cttnb, anticorps CG3637, anticorps Dmel\CG3637, anticorps cortactin, anticorps cttn, anticorps CTTN1, anticorps P85.25, anticorps Cttn, anticorps ems1, anticorps CTTN, anticorps cortactin, anticorps CG3637 gene product from transcript CG3637-RD, anticorps cortactin S homeolog, anticorps cortactin L homeolog, anticorps src substrate cortactin, anticorps Src substrate cortactin, anticorps CTTN, anticorps Cttn, anticorps Cortactin, anticorps cttn.S, anticorps cttn.L, anticorps cttn, anticorps CpipJ_CPIJ006351, anticorps Bm1_57220, anticorps LOC100533277
Sujet
SRC8 (CTTN) is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This protein has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this protein contributes to tumor cell invasion and metastasis.Synonyms: Amplaxin, CTTN, EMS1, Oncogene EMS1
ID gène
2017
NCBI Accession
NP_005222
Pathways
Signalisation MAPK
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