Cyclin H anticorps (C-Term)

N° du produit ABIN951760

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin H dans WB, FACS et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Cyclin H anticorps (C-Term) (ABIN951760)

Antigène: Cyclin H (CCNH)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin H est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Détail du produit anti-Cyclin H anticorps

Épitope: AA 267-299, C-Term

Specificité: This antibody reacts to CCNH.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 267-299 amino acids from the C-terminal region of human CCNH

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Cyclin H

Antigène: Cyclin H (CCNH)

Autre désignation: Cyclin H

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.Synonyms: CCNH, Cyclin-H, MO15-associated protein, p34, p37

Poids moléculaire: 37643 Da

ID gène: 902

NCBI Accession: NP_001230

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase