FDPS anticorps (N-Term)

N° du produit ABIN952387

Cet anticorps Lapin Polyclonal détecte spécifiquement FDPS dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour FDPS anticorps (N-Term) (ABIN952387)

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FDPS est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-FDPS anticorps

Épitope: AA 53-82, N-Term

Specificité: This antibody reacts to FDPS.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human FDPS

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FDPS

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Autre désignation: FPP Synthetase

Sujet: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: FDPS, FPS, Farnesyl diphosphate synthase, Farnesyl pyrophosphate synthetase, KIAA1293

Poids moléculaire: 48275 Da

ID gène: 2224

NCBI Accession: NP_001129293

Pathways: Regulation of Muscle Cell Differentiation