FZD6 anticorps (Middle Region)

N° du produit ABIN952410

Détail du produit anti-FZD6 anticorps

Antigène: FZD6 (Frizzled Family Receptor 6 (FZD6))

Épitope: AA 493-520, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD6 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human FZD6 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 493-520 amino acids from the Central region of human FZD6

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FZD6

Antigène: FZD6 (Frizzled Family Receptor 6 (FZD6))

Autre désignation: FZD6 (FZD6 Produits)

Synonymes: anticorps zgc:65879, anticorps zgc:77440, anticorps fz6, anticorps frz6, anticorps Xfrz6, anticorps frizzled6, anticorps frizzled-6, anticorps FZ-6, anticorps FZ6, anticorps HFZ6, anticorps NDNC10, anticorps Frizzled-6, anticorps Fz6, anticorps frizzled class receptor 6, anticorps frizzled class receptor 6 S homeolog, anticorps fzd6, anticorps fzd6.S, anticorps FZD6, anticorps Fzd6

Sujet: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.Synonyms: Frizzled-6, Fz-6, hFz6

Poids moléculaire: 79292 Da

ID gène: 8323

NCBI Accession: NP_001158087

Pathways: Signalisation WNT, Tube Formation