GLIS2 anticorps (Middle Region)

N° du produit ABIN952526

L’anticorps Lapin Polyclonal anti-GLIS2 a été validé pour WB et EIA. Il convient pour détecter GLIS2 dans des échantillons de Humain.

Aperçu rapide pour GLIS2 anticorps (Middle Region) (ABIN952526)

Antigène: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLIS2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-GLIS2 anticorps

Épitope: AA 172-202, Middle Region

Specificité: This antibody recognizes Human GLIS2 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 172-202 amino acids from the Central region of Human GLIS2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GLIS2

Antigène: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Autre désignation: GLIS2

Sujet: This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.Synonyms: GLI-similar 2, NKL, Neuronal Krueppel-like protein, Zinc finger protein GLIS2

Poids moléculaire: 55689 Da

ID gène: 84662

NCBI Accession: NP_115964