Glypican 3 anticorps (C-Term)

N° du produit ABIN952555

Cet anticorps Lapin Polyclonal détecte spécifiquement Glypican 3 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Glypican 3 anticorps (C-Term) (ABIN952555)

Antigène: Glypican 3 (GPC3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glypican 3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Glypican 3 anticorps

Épitope: AA 464-494, C-Term

Specificité: This antibody reacts to GPC3.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 464-494 amino acids from the C-terminal region of human GPC3

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Glypican 3

Antigène: Glypican 3 (GPC3)

Autre désignation: Glypican-3 / GPC3

Sujet: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.Synonyms: GTR2-2, Intestinal protein OCI-5, MXR7, OCI5

Poids moléculaire: 65563 Da

ID gène: 2719

NCBI Accession: NP_004475

Pathways: Glycosaminoglycan Metabolic Process