MED14 anticorps (Middle Region)

N° du produit ABIN953367

Cet anticorps anti-MED14 est un anticorps Lapin Polyclonal détectant MED14 dans WB et EIA. Adapté pour Humain et Souris.

Aperçu rapide pour MED14 anticorps (Middle Region) (ABIN953367)

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED14 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-MED14 anticorps

Épitope: AA 585-615, Middle Region

Specificité: This antibody recognizes Human and Mouse MED14 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 585-615 amino acids from the Central region of human MED14

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MED14

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Autre désignation: MED14

Sujet: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.Synonyms: ARC150, Activator-recruited cofactor 150 kDa component, CRSP complex subunit 2, CRSP2, CXorf4, Cofactor required for Sp1 transcriptional activation subunit 2, DRIP150, EXLM1, Mediator of RNA polymerase II transcription subunit 14, RGR1, TRAP170 Mediator complex 14, Thyroid hormone receptor-associated protein complex 170 kDa component, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component

Poids moléculaire: 160607 Da

ID gène: 9282

NCBI Accession: NP_004220

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha