MGMT anticorps (N-Term)

N° du produit ABIN953415

Cet anticorps anti-MGMT est un anticorps Lapin Polyclonal détectant MGMT dans WB et EIA. Adapté pour Humain.

Aperçu rapide pour MGMT anticorps (N-Term) (ABIN953415)

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MGMT est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-MGMT anticorps

Épitope: AA 1-30, N-Term

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: Synthetic peptide (between 1-30 aa) - KLH conjugated - corresponding to the N-terminal region of human MGMT.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MGMT

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Autre désignation: MGMT

Sujet: MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. It repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.Synonyms: 6-O-methylguanine-DNA methyltransferase, Methylated-DNA-protein-cysteine methyltransferase, O-6-methylguanine-DNA-alkyltransferase

ID gène: 9606

Pathways: Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus