anticorps FPG1, anticorps NEI1, anticorps hFPG1, anticorps 2810450N13Rik, anticorps Nei1, anticorps nei-like DNA glycosylase 1, anticorps nei like DNA glycosylase 1, anticorps nei endonuclease VIII-like 1 (E. coli), anticorps Neil1, anticorps NEIL1
Sujet
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).Synonyms: DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Endonuclease VIII-like 1, FPG1, NEH1