WHSC2 anticorps (Middle Region)

N° du produit ABIN953645

L’anticorps anti-WHSC2 Polyclonal Lapin est utilisé pour la détection de WHSC2 dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour WHSC2 anticorps (Middle Region) (ABIN953645)

Antigène: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WHSC2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-WHSC2 anticorps

Épitope: AA 261-290, Middle Region

Specificité: This antibody detects NELF-A (Center).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 261-290 amino acids from the Central region of human WHSC2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Détails sur WHSC2

Antigène: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Autre désignation: NELF-A

Sujet: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.Synonyms: NELFA, Negative elongation factor A, P/OKcl.15, WHSC2

ID gène: 7469

NCBI Accession: NP_005654

Pathways: Chromatin Binding