Nibrin anticorps (C-Term)

N° du produit ABIN953701

Cet anticorps Lapin Polyclonal détecte spécifiquement Nibrin dans WB, IF, FACS et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Nibrin anticorps (C-Term) (ABIN953701)

Antigène: Nibrin (NBN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nibrin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Détail du produit anti-Nibrin anticorps

Épitope: AA 609-638, C-Term

Specificité: This antibody recognizes Human Nibrin (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 609-638 amino acids from the C-terminal region of Human Nibrin Genename: NBN

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Nibrin

Antigène: Nibrin (NBN)

Autre désignation: Nibrin

Sujet: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.Synonyms: Cell cycle regulatory protein p95, NBN, NBS, NBS1, Nijmegen breakage syndrome protein 1, P95

Poids moléculaire: 84959 Da

ID gène: 4683

NCBI Accession: NP_002476

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response