PAK6 anticorps (Middle Region)

N° du produit ABIN953980

Cet anticorps Lapin Polyclonal détecte spécifiquement PAK6 dans WB, IHC (p), IF et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour PAK6 anticorps (Middle Region) (ABIN953980)

Antigène: PAK6 (P21-Activated Kinase 6 (PAK6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-PAK6 anticorps

Épitope: AA 275-305, Middle Region

Specificité: This antibody recognizes Human PAK6 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 275-305 amino acids from the Central region of human PAK6

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PAK6

Antigène: PAK6 (P21-Activated Kinase 6 (PAK6))

Autre désignation: PAK6

Sujet: This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].Synonyms: PAK-5, PAK-6, PAK5, Serine/threonine-protein kinase PAK 6, p21-activated kinase 6

Poids moléculaire: 74869 Da

ID gène: 56924

NCBI Accession: NP_001122100