PDE1B anticorps (C-Term)

N° du produit ABIN954063

Cet anticorps anti-PDE1B Polyclonal Lapin (ABIN954063) détecte spécifiquement PDE1B dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour PDE1B anticorps (C-Term) (ABIN954063)

Antigène: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-PDE1B anticorps

Épitope: AA 480-508, C-Term

Specificité: This antibody recognizes Human and Mouse PDE1B (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 480-508 amino acids from the C-terminal region of Human PDE1B

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PDE1B

Antigène: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Autre désignation: PDE1B

Sujet: Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).Synonyms: 5'-cyclic nucleotide phosphodiesterase 1B, 63 kDa Cam-PDE, Calcium/calmodulin-dependent 3', Cam-PDE 1B, PDE1B1, PDES1B, Phosphodiesterase 1B, Phosphodiesterase-1B calmodulin-dependent

Poids moléculaire: 61380 Da

ID gène: 5153

NCBI Accession: NP_000915

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma