PITRM1 anticorps (Middle Region)

N° du produit ABIN954153

Cet anticorps anti-PITRM1 Polyclonal Lapin (ABIN954153) détecte spécifiquement PITRM1 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PITRM1 anticorps (Middle Region) (ABIN954153)

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PITRM1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PITRM1 anticorps

Épitope: AA 497-526, Middle Region

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 497-526 amino acids from the Central region of human PITRM1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PITRM1

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Autre désignation: PITRM1

Sujet: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.Synonyms: KIAA1104, MP1, Metalloprotease 1, Pitrilysin metalloproteinase 1, Presequence protease mitochondrial

Poids moléculaire: 117455 Da

ID gène: 9606

Pathways: Signalisation PI3K-Akt, SARS-CoV-2 Protein Interactome