S100A9 anticorps (PE)
Aperçu rapide pour S100A9 anticorps (PE) (ABIN954657)
Antigène
Voir toutes S100A9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody Binds to Human Calgranulin B (S100A9). Other species not tested.
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Purification
- Protein G Chromatography of Ascitic fluid.
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Immunogène
- Purified granulocyte antigen of Human origin.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- DO NOT FREEZE!
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- S100A9 (S100 Calcium Binding Protein A9 (S100A9))
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Autre désignation
- S100A9 / Calgranulin-B / MRP14
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Sujet
- Calgranulin B, also known as MRP-14 and S100A9 is a member of the S100 family of proteins containing 2 EF hand (alpha helix, turn, alpha helix structure) calcium binding motifs. S100 proteins are localized in the cytoplasm and /or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. MRP-14 (S100A9) forms a heterodimeric complex with MRP-8 (S100A8) in the cytosol of monocyte and neutrophil cell types circulating in peripheral blood. Calgranulin B is found in elevated levels in the serum of cystic fibrosis cases and is also expressed in the skin of patients with psoriasis, eczematous dermatitis and squamous cell carcinoma. Calgranulin B is also expressed on macrophages in acute inflamed tissues (peridontitis, contact excema).Synonyms: CAGB, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, MRP-14, Migration inhibitory factor-related protein 14, S100 calcium-binding protein A9, S100-A9
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ID gène
- 6280
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NCBI Accession
- NP_002956
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UniProt
- P06702
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Pathways
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
Antigène
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