TFAM anticorps (C-Term)

N° du produit ABIN955168

Cet anticorps Lapin Polyclonal détecte spécifiquement TFAM dans WB, IF, IHC (p), FACS et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour TFAM anticorps (C-Term) (ABIN955168)

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAM est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Détail du produit anti-TFAM anticorps

Épitope: AA 223-254, C-Term

Specificité: This antibody detects TFAM (C-term).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Détails sur TFAM

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Autre désignation: TFAM / TCF6

Sujet: This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.Synonyms: Mitochondrial transcription factor 1, MtTF1, TCF-6, TCF6L2, Transcription factor 6, Transcription factor 6-like 2, mitochondrial Transcription factor A

ID gène: 7019

NCBI Accession: NP_003192

Pathways: Chromatin Binding