Uroplakin 1B anticorps (C-Term)
Aperçu rapide pour Uroplakin 1B anticorps (C-Term) (ABIN955481)
Antigène
Voir toutes Uroplakin 1B (UPK1B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 159-188, C-Term
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Specificité
- This antibody detects Uroplakin-1b (UPK1B) (C-term).
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Protein A column followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 159-188 amino acids from the C-terminal region of human UPK1B
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- Uroplakin 1B (UPK1B)
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Autre désignation
- Uroplakin-1b (UPK1B)
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Sujet
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq].Synonyms: TSPAN20, Tetraspanin-20, Tspan-20, UP1b, UPIb, Uroplakin Ib
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ID gène
- 7348
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NCBI Accession
- NP_008883
Antigène
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