Purified by antigen-specific affinity chromatography.
Immunogène
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human FACL3(long-chain fatty-acid-Coenzyme A ligase 3)
Acsl3
Reactivité: Humain, Souris, Rat
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions
For Research Use only
Format
Liquid
Buffer
This antibody is stored in PBS, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Minekura, Kang, Inagaki, Suzuki, Sato, Fujino, Yamamoto: "Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene." dans: Gene, Vol. 278, Issue 1-2, pp. 185-92, (2001) (PubMed).
Minekura, Fujino, Kang, Fujita, Endo, Yamamoto: "Human acyl-coenzyme A synthetase 3 cDNA and localization of its gene (ACS3) to chromosome band 2q34-q35." dans: Genomics, Vol. 42, Issue 1, pp. 180-1, (1997) (PubMed).
Fujino, Kang, Suzuki, Iijima, Yamamoto: "Molecular characterization and expression of rat acyl-CoA synthetase 3." dans: The Journal of biological chemistry, Vol. 271, Issue 28, pp. 16748-52, (1996) (PubMed).
Rose, King, Summers, Palmer, Yang, Wilkie, Reardon, Malcolm, Winter: "Localization of the genetic locus for Saethre-Chotzen syndrome to a 6 cM region of chromosome 7 using four cases with apparently balanced translocations at 7p21.2." dans: Human molecular genetics, Vol. 3, Issue 8, pp. 1405-8, (1995) (PubMed).
Brueton, van Herwerden, Chotai, Winter: "The mapping of a gene for craniosynostosis: evidence for linkage of the Saethre-Chotzen syndrome to distal chromosome 7p." dans: Journal of medical genetics, Vol. 29, Issue 10, pp. 681-5, (1992) (PubMed).
Antigène
Acsl3
(Acyl-CoA Synthetase Long-Chain Family Member 3 (Acsl3))
anticorps ACSL3, anticorps acsl3, anticorps fa07a08, anticorps im:7155129, anticorps si:dkey-20f20.5, anticorps wu:fa07a08, anticorps wu:fb34c03, anticorps si:dkeyp-109h9.2, anticorps ACS3, anticorps FACL3, anticorps PRO2194, anticorps 2610510B12Rik, anticorps Acs3, anticorps C85929, anticorps Facl3, anticorps Pro2194, anticorps F15H21.7, anticorps F15H21_7, anticorps long-chain acyl-CoA synthetase 3, anticorps acyl-CoA synthetase long-chain family member 3, anticorps acyl-CoA synthetase long chain family member 3, anticorps acyl-CoA synthetase long chain family member 3b, anticorps acyl-CoA synthetase long chain family member 3a, anticorps AcsL3, anticorps AMP-dependent synthetase and ligase family protein, anticorps ACSL3, anticorps acsl3b, anticorps acsl3a, anticorps acsL3, anticorps acsl3, anticorps Acsl3, anticorps LACS3
Sujet
The FACL3(long-chain fatty-acid-Coenzyme A ligase 3) is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog.