Angiopoietin 1 anticorps (Middle Region)

N° du produit ABIN965551

Cet anticorps Lapin Polyclonal détecte spécifiquement Angiopoietin 1 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour Angiopoietin 1 anticorps (Middle Region) (ABIN965551)

Antigène: Angiopoietin 1 (ANGPT1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Angiopoietin 1 anticorps

Épitope: Middle Region

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Angiopoietin-1 (ANGPT1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human ANG1 , different from the related mouse sequence by two amino acids, and different from the related rat sequence by only one amino acid.< br/>Immunogen was affinity purified.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

Références pour anticorps anti-Angiopoietin 1 (ABIN965551)

Compston: "Selective oestrogen receptor modulators: potential therapeutic applications." dans: Clinical endocrinology, Vol. 48, Issue 4, pp. 389-91, (1998) (PubMed).

Cheung, Stewart, Marsden: "Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23." dans: Genomics, Vol. 48, Issue 3, pp. 389-91, (1998) (PubMed).

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: Angiopoietin-1(ANG-1)

Sujet: Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22. 3-q23 and 8p23.

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process