AXL anticorps (AA 466-530)

N° du produit ABIN965629

Cet anticorps Souris Monoclonal détecte spécifiquement AXL dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 3+ publications.

Aperçu rapide pour AXL anticorps (AA 466-530) (ABIN965629)

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AXL est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1B3A2

Détail du produit anti-AXL anticorps

Épitope: AA 466-530

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-AXL (ABIN965629)

Collett, Sage, Kirton, Alexander, Gilmore, Canfield: "Axl/phosphatidylinositol 3-kinase signaling inhibits mineral deposition by vascular smooth muscle cells." dans: Circulation research, Vol. 100, Issue 4, pp. 502-9, (2007) (PubMed).

Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: "Towards a proteome-scale map of the human protein-protein interaction network. ..." dans: Nature, Vol. 437, Issue 7062, pp. 1173-8, (2005) (PubMed).

Budagian, Bulanova, Orinska, Duitman, Brandt, Ludwig, Hartmann, Lemke, Saftig, Bulfone-Paus: "Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum." dans: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9324-39, (2005) (PubMed).

Détails sur AXL

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Autre désignation: AXL

Sujet: AXL receptor tyrosine kinase. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms: UFO, JTK11

ID gène: 558

Pathways: Signalisation RTK, Cellular Response to Molecule of Bacterial Origin