AXL anticorps (C-Term)

N° du produit ABIN965631

Cet anticorps anti-AXL est un anticorps Lapin Polyclonal détectant AXL dans IHC. Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 6+ publications.

Aperçu rapide pour AXL anticorps (C-Term) (ABIN965631)

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AXL est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-AXL anticorps

Épitope: C-Term

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human AXL(Tyrosine-protein kinase receptor UFO)

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Références pour anticorps anti-AXL (ABIN965631)

Shimojima, Takada, Ebihara, Neumann, Fujioka, Irimura, Jones, Feldmann, Kawaoka: "Tyro3 family-mediated cell entry of Ebola and Marburg viruses." dans: Journal of virology, Vol. 80, Issue 20, pp. 10109-16, (2006) (PubMed).

Craven, Xu, Weiner, Fridell, Dent, Srivastava, Varnum, Liu, Cance: "Receptor tyrosine kinases expressed in metastatic colon cancer." dans: International journal of cancer. Journal international du cancer, Vol. 60, Issue 6, pp. 791-7, (1995) (PubMed).

Lee, Strunk, Spritz: "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes." dans: Oncogene, Vol. 8, Issue 12, pp. 3403-10, (1993) (PubMed).

Partanen, Mäkelä, Alitalo, Lehväslaiho, Alitalo: "Putative tyrosine kinases expressed in K-562 human leukemia cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 22, pp. 8913-7, (1991) (PubMed).

OBryan, Frye, Cogswell, Neubauer, Kitch, Prokop, Espinosa, Le Beau, Earp, Liu: "axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase." dans: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5016-31, (1991) (PubMed).

Janssen, Schulz, Steenvoorden, Schmidberger, Strehl, Ambros, Bartram: "A novel putative tyrosine kinase receptor with oncogenic potential." dans: Oncogene, Vol. 6, Issue 11, pp. 2113-20, (1991) (PubMed).

Détails sur AXL

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Autre désignation: AXL

Sujet: AXL(Tyrosine-protein kinase receptor UFO) may function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, AXL seems to function as a cell entry factor. AXL is heterodimer and heterotetramer with GAS6. AXL is a single-pass type I membrane protein. It is highly expressed in metastatic colon tumors. And weakly expressed in normal colon tissue. AXL belongs to the protein kinase superfamily and Tyr protein kinase family and AXL/UFO subfamily. AXL contains 1 protein kinase domain.
Synonyms: UFO

Pathways: Signalisation RTK, Cellular Response to Molecule of Bacterial Origin