Beclin 1 anticorps

N° du produit ABIN965657

L’anticorps Souris Monoclonal anti-Beclin 1 a été validé pour WB, ELISA, IHC et FACS. Il convient pour détecter Beclin 1 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour Beclin 1 anticorps (ABIN965657)

Antigène: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Beclin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2A4

Détail du produit anti-Beclin 1 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human BECN1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Beclin 1 (ABIN965657)

Pickford, Masliah, Britschgi, Lucin, Narasimhan, Jaeger, Small, Spencer, Rockenstein, Levine, Wyss-Coray: "The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice." dans: The Journal of clinical investigation, Vol. 118, Issue 6, pp. 2190-9, (2008) (PubMed).

Détails sur Beclin 1

Antigène: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Autre désignation: BECN1

Sujet: Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 (PubMed 19270693)).(supplied by OMIM).
Tissue specificity: Ubiquitous.
Synonyms: ATG6, VPS30, beclin1, BECN1

Poids moléculaire: 60kDa

ID gène: 8678

Pathways: Autophagy