CD14 anticorps

N° du produit ABIN965766

Cet anticorps anti-CD14 est un anticorps Monoclonal détectant CD14 dans IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour CD14 anticorps (ABIN965766)

Antigène: CD14

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-CD14 anticorps

Specificité: Ni-NTA purified recombinant human CD14 expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein G affinity chromatography.

Isotype: IgG1

Information d'application

Indications d'application: IHC: Dilution 1:200-1:400
ELISA: Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.2%BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.

ID gène: 929

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades