CDK1 anticorps

N° du produit ABIN965841

Cet anticorps anti-CDK1 est un anticorps Souris Monoclonal détectant CDK1 dans WB et ELISA. Adapté pour Humain, Souris, Rat et Singe. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour CDK1 anticorps (ABIN965841)

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2G9

Détail du produit anti-CDK1 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CDK1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-CDK1 (ABIN965841)

McMullin: "The classification and diagnosis of erythrocytosis." dans: International journal of laboratory hematology, Vol. 30, Issue 6, pp. 447-59, (2008) (PubMed).

Marash, Liberman, Henis-Korenblit, Sivan, Reem, Elroy-Stein, Kimchi: "DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis." dans: Molecular cell, Vol. 30, Issue 4, pp. 447-59, (2008) (PubMed).

Détails sur CDK1

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Autre désignation: CDK1

Sujet: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Synonyms: CDC2, CDC28A, P34CDC2, MGC111195, DKFZp686L20222, CDK1

Poids moléculaire: 34kDa

ID gène: 983

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA