Purified by antigen-specific affinity chromatography.
Immunogène
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DUSP6(Dual specificity protein phosphatase 6)
DUSP6
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC, IF, ICC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions
For Research Use only
Format
Liquid
Buffer
This antibody is stored in PBS, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Furukawa, Yatsuoka, Youssef, Abe, Yokoyama, Fukushige, Soeda, Hoshi, Hayashi, Sunamura, Kobari, Horii: "Genomic analysis of DUSP6, a dual specificity MAP kinase phosphatase, in pancreatic cancer." dans: Cytogenetics and cell genetics, Vol. 82, Issue 3-4, pp. 156-9, (1999) (PubMed).
Groom, Sneddon, Alessi, Dowd, Keyse: "Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase." dans: The EMBO journal, Vol. 15, Issue 14, pp. 3621-32, (1996) (PubMed).
DUSP6 (Dual specificity protein phosphatase 6) inactivates MAP kinases. DUSP6 has a specificity for the ERK family and it belongs to the protein-tyrosine phosphatase family and non-receptor class dual specificity subfamily. DUSP6 contains 1 rhodanese domain and 1 tyrosine-protein phosphatase domain.