FGF7 anticorps (N-Term)

N° du produit ABIN966138

Cité dans 2 publications. Cet anticorps anti-FGF7 Polyclonal (ABIN966138) détecte spécifiquement FGF7 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FGF7 anticorps (N-Term) (ABIN966138)

Antigène: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FGF7 anticorps

Épitope: AA 51-65, N-Term

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminal of human FGF7 (51-65aa), identical to the related mouse and rat sequence.

Information d'application

Indications d'application: WB: The detection limit for FGF7 is approximately 5ng/lane under non-reducing and reducing conditions.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Stock: -20 °C

Références pour anticorps anti-FGF7 (ABIN966138)

Eberlé, Dubreuil, Mattei, Devilard, Lopez: "The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH gene." dans: Gene, Vol. 159, Issue 2, pp. 267-72, (1995) (PubMed).

Kelley, Pech, Seuanez, Rubin, OBrien, Aaronson: "Emergence of the keratinocyte growth factor multigene family during the great ape radiation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 19, pp. 9287-91, (1992) (PubMed).

Détails sur FGF7

Antigène: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Autre désignation: FGF7

Sujet: Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway