Interferon gamma anticorps

N° du produit ABIN966336

Cet anticorps anti-Interferon gamma est un anticorps Monoclonal détectant Interferon gamma dans WB et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Interferon gamma anticorps (ABIN966336)

Antigène: Interferon gamma (IFNG)

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp Interferon gamma est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Interferon gamma anticorps

Specificité: Ni-NTA purified recombinant human IFN-gamma expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-Interferon gamma (ABIN966336)

Tsubota, Fukagawa, Fujihara, Shimmura, Saito, Saito, Takeuchi: "Regulation of human leukocyte antigen expression in human conjunctival epithelium." dans: Investigative ophthalmology & visual science, Vol. 40, Issue 1, pp. 28-34, (1999) (PubMed).

Détails sur Interferon gamma

Antigène: Interferon gamma (IFNG)

Autre désignation: IFN-Y

Sujet: Interferon-gamma (IFN-gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.

ID gène: 3458

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy