IRS1 anticorps

N° du produit ABIN966417

Cité dans 4 publications. Cet anticorps anti-IRS1 Polyclonal Lapin (ABIN966417) détecte spécifiquement IRS1 dans IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IRS1 anticorps (ABIN966417)

Antigène: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRS1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-IRS1 anticorps

Specificité: IRS-1 (Ab-307) antibody detects endogenous levels of total IRS-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 307.

Information d'application

Indications d'application: IHC: 1:50-1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-IRS1 (ABIN966417)

Tuncman, Hirosumi, Solinas, Chang, Karin, Hotamisligil: "Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 28, pp. 10741-6, (2006) (PubMed).

Shoelson, Lee, Goldfine: "Inflammation and insulin resistance." dans: The Journal of clinical investigation, Vol. 116, Issue 7, pp. 1793-801, (2006) (PubMed).

Steppan, Wang, Whiteman, Birnbaum, Lazar: "Activation of SOCS-3 by resistin." dans: Molecular and cellular biology, Vol. 25, Issue 4, pp. 1569-75, (2005) (PubMed).

Frolov, Drozdova, Kazanskaia, Ramdavon: "[The synchronization and desynchronization of the" dans: Biulleten' eksperimental'noĭ biologii i meditsiny, Vol. 116, Issue 7, pp. 17-9, (1993) (PubMed).

Détails sur IRS1

Antigène: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Autre désignation: IRS-1

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process