OGG1 anticorps (8-Oxoguanine DNA Glycosylase) (C-Term)

Details for Product anti-OGG1 Antibody No. ABIN966715, Fournisseur: Connectez-vous pour afficher
Antigène
  • OGG1
  • zgc:158858
  • 8-oxoguanine-DNA glycosylase 1
  • ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1
  • ATOGG1
  • F8K7.14
  • F8K7_14
  • 19.m02329
  • DDBDRAFT_0184479
  • DDBDRAFT_0233024
  • DDB_0184479
  • DDB_0233024
  • ogg1
  • Tb04.1H19.930
  • HMMH
  • HOGG1
  • MUTM
  • OGH1
  • Mmh
  • 8-oxoguanine DNA glycosylase
  • 8-oxoguanine DNA glycosylase L homeolog
  • 8-oxoguanine-DNA glycosylase 1
  • 8-OXOGUANINE DNA GLYCOSYLASE
  • putative 8-oxoguanine DNA glycosylase
  • 8-oxoguanine DNA-glycosylase
  • N-glycosylase/DNA lyase OGG1
  • 8-oxoguanine DNA-glycosylase 1
  • OGG1
  • ogg1.L
  • ogg1
  • ECU08_0770
  • CA_C2707
  • BBOV_I004290
  • Smp_074010.1
  • LOC9329243
  • Tb927.4.2480
  • Ogg1
Épitope
C-Term
45
8
7
7
6
4
4
3
3
1
1
1
1
Reactivité
Humain
124
66
64
12
3
2
2
1
1
Hôte
Lapin
80
44
21
Clonalité
Polyclonal
Conjugué
Cet anticorp OGG1 est non-conjugé
8
8
6
4
4
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
87
73
46
44
43
42
39
13
12
7
2
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human OGG1 (N-glycosylase/DNA lyase)
Autre désignation OGG1 (OGG1 Antibody Extrait)
Sujet DNA repair enzyme that incises DNA at 8-oxoG residues. OGG1 (N-glycosylase/DNA lyase) excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-Nmethylformamidopyrimidine (FAPY) from damaged DNA. OGG1 has a beta-lyase activity that nicks DNA 3' to the lesion. Defects in OGG1 are associated with tumor formation.Defects in OGG1 are a cause of renal cell carcinoma OGG1 belongs to the type-1 OGG1 family.
Synonyms: MMH, MUTM, OGH1
Pathways Réparation de l'ADN
Restrictions For Research Use only
Produit citée dans: Aburatani, Hippo, Ishida, Takashima, Matsuba, Kodama, Takao, Yasui, Yamamoto, Asano: "Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue." dans: Cancer research, Vol. 57, Issue 11, pp. 2151-6, 1997 (PubMed).

Rosenquist, Zharkov, Grollman: "Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 14, pp. 7429-34, 1997 (PubMed).

Roldán-Arjona, Wei, Carter, Klungland, Anselmino, Wang, Augustus, Lindahl: "Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 15, pp. 8016-20, 1997 (PubMed).

Kuo, Sklar: "Augmented expression of a human gene for 8-oxoguanine DNA glycosylase (MutM) in B lymphocytes of the dark zone in lymph node germinal centers." dans: The Journal of experimental medicine, Vol. 186, Issue 9, pp. 1547-56, 1997 (PubMed).

Bjorâs, Luna, Johnsen, Hoff, Haug, Rognes, Seeberg: "Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites." dans: The EMBO journal, Vol. 16, Issue 20, pp. 6314-22, 1997 (PubMed).

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