CDKN1B anticorps (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1))

Details for Product anti-CDKN1B Antibody No. ABIN966734, Fournisseur: Connectez-vous pour afficher
Antigène
  • CDKN4
  • KIP1
  • MEN1B
  • MEN4
  • P27KIP1
  • cdkn1b
  • sb:cb611
  • wu:fb63g10
  • wu:fb64g10
  • wu:fe18e03
  • CDKN1B
  • Kip1
  • p27
  • Cdki1b
  • AA408329
  • AI843786
  • p27Kip1
  • cdkn1bl
  • cyclin dependent kinase inhibitor 1B
  • cyclin-dependent kinase inhibitor 1Bb
  • cyclin-dependent kinase inhibitor 1B
  • cyclin-dependent kinase inhibitor 1Ba
  • CDKN1B
  • cdkn1bb
  • Cdkn1b
  • cdkn1ba
Reactivité
Humain, Souris, Rat (Rattus)
791
439
375
182
42
24
18
8
8
7
3
3
2
1
1
1
Hôte
Lapin
481
308
37
2
2
1
Clonalité
Polyclonal
Conjugué
Cet anticorp CDKN1B est non-conjugé
41
36
35
34
34
29
9
8
8
6
6
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (IHC)
631
338
243
232
202
198
102
97
84
55
39
28
14
7
5
3
1
1
1
Options
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Immunogène The antiserum was produced against synthesized non-phosphopeptide derived from human p27Kip1 around the phosphorylation site of serine 10 (N-G-SP-P-S).
Specificité P27Kip1 (Ab-10) antibody detects endogenous levels of total p27Kip1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Plasmids, Primers & others Plasmids, Primers & others CDKN1B products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation p27Kip1 (CDKN1B Antibody Extrait)
Pathways Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
Indications d'application WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Produit citée dans: Le, Claret, Lammayot, Tian, Deshpande, LaPushin, Tari, Bast: "The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition." dans: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23441-50, 2003 (PubMed).

Connor, Kotchetkov, Cariou, Resch, Lupetti, Beniston, Melchior, Hengst, Slingerland: "CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis." dans: Molecular biology of the cell, Vol. 14, Issue 1, pp. 201-13, 2003 (PubMed).

Chopra, Fernandez De Mattos, Lam, Mann: "Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1." dans: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 32413-6, 2002 (PubMed).

Boehm, Yoshimoto, Crook, Nallamshetty, True, Nabel, Nabel: "A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression." dans: The EMBO journal, Vol. 21, Issue 13, pp. 3390-401, 2002 (PubMed).

Background publications McAllister, Becker-Hapak, Pintucci, Pagano, Dowdy: "Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions." dans: Molecular and cellular biology, Vol. 23, Issue 1, pp. 216-28, 2002 (PubMed).

Avez-vous cherché autre chose?