SAPK, JNK anticorps

N° du produit ABIN966993

Cité dans 3 publications. Cet anticorps anti-SAPK, JNK Polyclonal Lapin (ABIN966993) détecte spécifiquement SAPK, JNK dans IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SAPK, JNK anticorps (ABIN966993)

Antigène: SAPK, JNK

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC)

Détail du produit

Specificité: SAPK/JNK (Ab-185) antibody detects endogenous levels of total SAPK/JNK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human SAPK/JNK around the phosphorylation site of tyrosine 185(T-P-YP-V-V).

Information d'application

Indications d'application: IHC: 1:50-1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Référence

Matsuyoshi, Shimada, Nakamura, Ishida, Konishi: "FADD phosphorylation is critical for cell cycle regulation in breast cancer cells." dans: British journal of cancer, Vol. 94, Issue 4, pp. 532-9, (2006) (PubMed).

Ouwens, de Ruiter, van der Zon, Carter, Schouten, van der Burgt, Kooistra, Bos, Maassen, van Dam: "Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38." dans: The EMBO journal, Vol. 21, Issue 14, pp. 3782-93, (2002) (PubMed).

Guan, Buckman, Springer, Morrison: "Both p38alpha(MAPK) and JNK/SAPK pathways are important for induction of nitric-oxide synthase by interleukin-1beta in rat glomerular mesangial cells." dans: The Journal of biological chemistry, Vol. 274, Issue 51, pp. 36200-6, (2000) (PubMed).

Détail du antigène

Antigène: SAPK, JNK

Autre désignation: SAPK/JNK