FKBP10 anticorps (AA 434-576)

N° du produit ABIN968087

L’anticorps Souris Monoclonal anti-FKBP10 a été validé pour WB, IHC, IP et IF. Il convient pour détecter FKBP10 dans des échantillons de Humain, Souris et Rat. Il y a 2+ publications disponibles.

Aperçu rapide pour FKBP10 anticorps (AA 434-576) (ABIN968087)

Antigène: FKBP10 (FK506 Binding Protein 10, 65 KDa (FKBP10))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FKBP10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: 25-FKBP65

Détail du produit anti-FKBP10 anticorps

Épitope: AA 434-576

Réactivité croisée: Rat (Rattus), Humain

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Mouse FKBP65 aa. 434-576

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN967389, ABIN968539

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Références pour anticorps anti-FKBP10 (ABIN968087)

Patterson, Schaub, Coleman, Davis: "Developmental regulation of FKBP65. An ER-localized extracellular matrix binding-protein." dans: Molecular biology of the cell, Vol. 11, Issue 11, pp. 3925-35, (2001) (PubMed).

Coss, Winterstein, Sowder, Simek: "Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65)." dans: The Journal of biological chemistry, Vol. 270, Issue 49, pp. 29336-41, (1996) (PubMed).

Détails sur FKBP10

Antigène: FKBP10 (FK506 Binding Protein 10, 65 KDa (FKBP10))

Autre désignation: FKBP65

Sujet: FK506, one of multiple potent compounds that block T cell proliferation, is used for immunosuppressive therapy. Several FK506-binding proteins (FKBPs) have been identified in the search for intracellular targets for FK506. These include FKBP12, FKBP13, FKBP51, and FKBP52. The immunosuppressive effects of FK506 and FKBPs result from the inhibition of the calcineurin phosphatase, a well known component of the signaling cascade leading to IL-2 production. FKBP65 is another member of the FKBP protein family and contains the characteristic peptidylprolyl cis-trans-isomerase activity. FKBP65 has been reported to be expressed in the lung, testis, brain, heart, and spleen. Although it has a predicted molecular weight of 65 kDa, FKBP65 has been observed to migrate ranging from 68-72 kDa in SDS electrophoresis gels, perhaps, due to glycosylation and/or phosphorylation.
Synonyms: FK506 Binding Protein-65

Poids moléculaire: 68-72 kDa

Pathways: SARS-CoV-2 Protein Interactome