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RAC1 anticorps

Reactivité: Humain, Souris, Rat, Chien, Poulet WB, IHC, IF, IP Hôte: Souris Monoclonal 102-Rac1 unconjugated
N° du produit ABIN968088
  • Antigène Voir toutes RAC1 Anticorps
    RAC1
    Reactivité
    • 87
    • 49
    • 34
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Poulet
    Hôte
    • 78
    • 8
    • 1
    Souris
    Clonalité
    • 78
    • 9
    Monoclonal
    Conjugué
    • 39
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RAC1 est non-conjugé
    Application
    • 66
    • 26
    • 26
    • 25
    • 22
    • 12
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
     Réactivité croisée
    Poulet, Chien, Souris, Rat (Rattus)
    Attributs du produit
    Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Positive Control: Rat Cerebrum
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    102-Rac1
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product RAC1 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Aqueous buffered solution containing BSA, glycerol.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20°C.
  • Antigène
    RAC1
    Abstract
    RAC1 Produits
    Synonymes
    anticorps Rac-1, anticorps TC-25, anticorps p21-Rac1, anticorps AL023026, anticorps D5Ertd559e, anticorps RAC2, anticorps CRAC1A, anticorps rac1, anticorps wu:fd16e02, anticorps zgc:55823, anticorps zgc:55917, anticorps zgc:86934, anticorps 2248, anticorps CG2248, anticorps D-Rac, anticorps D-Rac 1, anticorps D-Rac1, anticorps DRac, anticorps DRac1, anticorps DRacA, anticorps Dm Rac1, anticorps DmRAC, anticorps DmRAC1, anticorps Dmel\CG2248, anticorps Dmrac1, anticorps Drac, anticorps Drac1, anticorps Drac1a, anticorps DracA, anticorps GTPase Rac1, anticorps P40792, anticorps RAC1, anticorps Rac, anticorps Rac GTPase, anticorps Rac3, anticorps RacA, anticorps dRac, anticorps dRac1, anticorps drac1, anticorps rac, anticorps Xrac, anticorps mig5, anticorps p21-rac1, anticorps tc-25, anticorps Rac family small GTPase 1, anticorps RAS-related C3 botulinum substrate 1, anticorps ras-related C3 botulinum toxin substrate 1, anticorps ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1), anticorps Rac family small GTPase 1a, anticorps CG2248 gene product from transcript CG2248-RB, anticorps Rac family small GTPase 1 L homeolog, anticorps ras homolog family member G, anticorps RAC1, anticorps Rac1, anticorps rac1a, anticorps rac1.L, anticorps RHOG
    Sujet
    Rac1 is a member of the expanding family of Ras-related GTPase proteins. These small proteins have the ability to switch between two different conformational states: the active (GTP-bound) and the inactive (GDP-bound). The GTPase activity is increased by specific activator proteins named GAPs. Rac1, contains the consensus sequence Cys-X-X-X-COOH, which localizes it to the plasma membrane. Growth factor stimulation of cells results in a dramatic reorganization of the actin filament network and membrane ruffling, processes for which Rac1 is essential. Constitutive expression of Rac1 leads to cell transformation. This process is mediated by the Rac1-dependent activation of the p65PAK serine/threonine kinase. IQGAP1 has been identified as a GTPase activating protein specific for Rac1.
    Testing in native ELISA with recombinant proteins to CDC42 and Rho have shown that the antibody to Rac1 (cat No ABIN968088/1) recognizes CDC42 and Rho. Due to sequence homology among various small GTPase familyl members, potential reactivity could be observed with other family members.
    Poids moléculaire
    21 kDa
    Pathways
    Signalisation WNT, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling
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