Cortactin anticorps

N° du produit ABIN969073

Cet anticorps Souris Monoclonal détecte spécifiquement Cortactin dans WB, IHC et ELISA. Il présente une réactivité envers Humain et Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour Cortactin anticorps (ABIN969073)

Antigène: Cortactin (CTTN)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cortactin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4C6

Détail du produit anti-Cortactin anticorps

Fonction: CTTN Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CTTN expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Cortactin (ABIN969073)

Li, Lin, Liu, Xie: "[Expression and clinical significance of EMS1 gene in gastric carcinoma]." dans: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 3, pp. 323-6, (2008) (PubMed).

Lin, Su, Tsai, Sheu, Jin: "Association of cortactin, fascin-1 and epidermal growth factor receptor (EGFR) expression in ovarian carcinomas: correlation with clinicopathological parameters." dans: Disease markers, Vol. 25, Issue 1, pp. 17-26, (2008) (PubMed).

Détails sur Cortactin

Antigène: Cortactin (CTTN)

Autre désignation: CTTN

Sujet: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. (provided by RefSeq)

Poids moléculaire: 80 kDa

UniProt: Q14247

Pathways: Signalisation MAPK