FLT4 anticorps

N° du produit ABIN969147

Cité dans 3 publications. Cet anticorps anti-FLT4 Monoclonal Souris (Clone 4H4) (ABIN969147) détecte spécifiquement FLT4 dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FLT4 anticorps (ABIN969147)

Antigène: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLT4 est non-conjugé

Application: ELISA

Clone: 4H4

Détail du produit anti-FLT4 anticorps

Fonction: FLT4 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human FLT4 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-FLT4 (ABIN969147)

Goodyear, Kheyfets, Garcia, Stearns: "Role of the VEGFR3/VEGFD receptor axis in TGFbeta1 activation of primary prostate cell lines." dans: The Prostate, Vol. 69, Issue 9, pp. 982-90, (2009) (PubMed).

Pan, Chang, Chang, Su, Wang, Hung: "Sumoylation of Prox1 controls its ability to induce VEGFR3 expression and lymphatic phenotypes in endothelial cells." dans: Journal of cell science, Vol. 122, Issue Pt 18, pp. 3358-64, (2009) (PubMed).

Jayasinghe, Simiantonaki, Michel-Schmidt, Kirkpatrick: "Endothelial VEGFR-3 expression in colorectal carcinomas is associated with hematogenous metastasis." dans: Oncology reports, Vol. 22, Issue 5, pp. 1093-100, (2009) (PubMed).

Détails sur FLT4

Antigène: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Autre désignation: FLT4

Sujet: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. Tissue specificity: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain. VEGFR-3 is induced in all endothelial cells (EC

Poids moléculaire: 145 kDa

ID gène: 2324

UniProt: P35916

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling