c-FOS anticorps

N° du produit ABIN969150

Cet anticorps anti-c-FOS est un anticorps Souris Monoclonal détectant c-FOS dans WB, ELISA, IHC et FACS. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour c-FOS anticorps (ABIN969150)

Antigène: c-FOS (c-Fos) (c-Fos)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp c-FOS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2G2

Détail du produit anti-c-FOS anticorps

Fonction: FOS Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human FOS expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-c-FOS (ABIN969150)

Das, Muniyappa: "c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1." dans: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 53-63, (2010) (PubMed).

Wang, Sun, Jiang, Zhang, Wolfl: "FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis." dans: Cancer investigation, Vol. 27, Issue 8, pp. 816-24, (2009) (PubMed).

Détails sur c-FOS

Antigène: c-FOS (c-Fos) (c-Fos)

Autre désignation: FOS

Sujet: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Poids moléculaire: 40.7 kDa

ID gène: 2353

UniProt: P01100

Pathways: S100 Proteins