ISL1 anticorps

N° du produit ABIN969219

Cet anticorps anti-ISL1 est un anticorps Souris Monoclonal détectant ISL1 dans ELISA, IHC et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour ISL1 anticorps (ABIN969219)

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ISL1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 1H9

Détail du produit anti-ISL1 anticorps

Fonction: ISL1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ISL1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ISL1 (ABIN969219)

Elshatory, Gan: "The LIM-homeobox gene Islet-1 is required for the development of restricted forebrain cholinergic neurons." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 13, pp. 3291-7, (2008) (PubMed).

Détails sur ISL1

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Autre désignation: ISL1

Sujet: ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Poids moléculaire: 39 kDa

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding