S100B anticorps

N° du produit ABIN969391

Cet anticorps Souris Monoclonal détecte spécifiquement S100B dans IHC et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour S100B anticorps (ABIN969391)

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100B est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 9A11B9

Détail du produit anti-S100B anticorps

Fonction: S100B Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of S100B expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-S100B (ABIN969391)

Zimmer, Chaplin, Baldwin, Rast: "S100-mediated signal transduction in the nervous system and neurological diseases." dans: Cellular and molecular biology (Noisy-le-Grand, France), Vol. 51, Issue 2, pp. 201-14, (2005) (PubMed).

Sorci, Riuzzi, Arcuri, Giambanco, Donato: "Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE binding." dans: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4880-94, (2004) (PubMed).

Shapiro, Marks, Whitaker-Azmitia: "Increased clusterin expression in old but not young adult S100B transgenic mice: evidence of neuropathological aging in a model of Down Syndrome." dans: Brain research, Vol. 1010, Issue 1-2, pp. 17-21, (2004) (PubMed).

Détails sur S100B

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Autre désignation: S100B

Sujet: S100B (S100 calcium binding protein B) is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S100B are present in a variety of other tissues, and calbindin is present in intestine and kidney. Parvalbumin B is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

ID gène: 6285

UniProt: P04271

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins