NCK1 anticorps

N° du produit ABIN969545

Détail du produit anti-NCK1 anticorps

Antigène: NCK1 (NCK Adaptor Protein 1 (NCK1))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NCK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human NCK1 expressed in E. coli.

Clone: 5B7

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-NCK1 (ABIN969545)

Preisinger, Kolch: "The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway." dans: Cellular signalling, Vol. 22, Issue 5, pp. 848-56, (2010) (PubMed).

Blasutig, New, Thanabalasuriar, Dayarathna, Goudreault, Quaggin, Li, Gruenheid, Jones, Pawson: "Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization." dans: Molecular and cellular biology, Vol. 28, Issue 6, pp. 2035-46, (2008) (PubMed).

Détails sur NCK1

Antigène: NCK1 (NCK Adaptor Protein 1 (NCK1))

Autre désignation: NCK1 (NCK1 Produits)

Synonymes: anticorps NCK, anticorps NCKalpha, anticorps nck-1, anticorps NCK1, anticorps 6330586M15Rik, anticorps D230010O13Rik, anticorps Nck, anticorps Nck-1, anticorps Nck1, anticorps nck, anticorps nck1-a, anticorps nck1-b, anticorps nckalpha, anticorps NCK adaptor protein 1, anticorps non-catalytic region of tyrosine kinase adaptor protein 1, anticorps NCK adaptor protein 1b, anticorps NCK adaptor protein 1 L homeolog, anticorps NCK1, anticorps Nck1, anticorps nck1b, anticorps nck1.L

Sujet:

Description: The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.

Aliases: NCK, nck-1, NCKalpha

Poids moléculaire: 47 kDa

ID gène: 4690

HGNC: 4690

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals